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T2499 |
Torcetrapib
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CP-529414 |
CETP
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Torcetrapib (CP-529414) is a cholesteryl ester transfer protein (CETP) inhibitor that reduces the heterotypic transfer of cholesteryl ester from HDL to LDL and/or VLDL. Torcetrapib failed in phase III trials due to exces... |
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T6262 |
Evacetrapib
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LY2484595 |
CETP
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Evacetrapib (LY2484595) (LY2484595) is a potent and selective inhibitor of CETP with IC50 of 5.5 nM, elevates HDL cholesterol without increases in aldosterone or blood pressure. Phase 3. |
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T1928 |
Anacetrapib
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MK-0859 |
CETP
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Anacetrapib (MK-0859) (MK0859) is an effective, specific, reversible rhCETP and mutant CETP(C13S) inhibitor (IC50: 7.9 nM and 11.8 nM). Anacetrapib reduces the transfer of cholesteryl ester from HDL to LDL and/or VLDL th... |
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T6048 |
Dalcetrapib
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JTT-705,RO4607381 |
CETP
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Dalcetrapib (RO4607381), a rhCETP inhibitor (IC50=0.2 μM), increases the plasma HDL cholesterol. |
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T28225 |
Obicetrapib
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TA8995,AMG899,Obicetrapib (free base),AMG 899,AMG-899,Obicetrapib,TA-8995 |
CETP
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Obicetrapib (AMG-899) is an inhibitor of cholesteryl ester transfer protein. |
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T68416 |
DRL-17822
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DRL-17822 is a Cholesteryl Ester Transfer Protein (CETP) inhibitor. |
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T68265 |
PF-04445597
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PF-04445597 is a potent, orally bioavailable inhibitor of cholesteryl ester transfer protein (CETP). |
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T14976 |
CKD-519
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Others
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CKD-519 is a selective inhibitor of cholesteryl ester transfer protein (CETP). It inhibits CETP-mediated transfer of cholesteryl ester in human serum (IC50: 2.3 nM). |
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T69672 |
MK-825
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MK-825 is a cholesteryl ester transfer protein (CETP) inhibitor. |
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T39137 |
CETP-IN-4
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CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor. |
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T36139 |
BMS-795311
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Potent cholesteryl ester transfer protein (CETP) inhibitor (IC50 = 4 nM in an enzyme-based scintillation proximity assay). Inhibits cholesteryl ester transfer and increases HDL-C levels in vivo. Orally bioavailable.
Qiao... |
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T13079 |
TAP311
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CETP
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TAP311 is an inhibitor of cholesteryl ester transfer protein (CETP)(IC50 of 62 nM). |
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T68505 |
Obicetrapib sodium
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Obicetrapib sodium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial ... |
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T68504 |
Obicetrapib calcium
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Obicetrapib calcium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible beneficial... |
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T68503 |
Obicetrapib potassium
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Obicetrapib potassium is a cholesteryl ester transfer protein (CETP) inhibitor. CETP inhibitors substantially increase the concentration of high-density lipoprotein cholesterol (HDL-C), which may have a possible benefici... |
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T38908 |
MK-8262
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MK-8262, an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor (IC 50 = 53 nM, log D = 5.3), is a bistrifluoromethyl analogue that shows promise in research related to high-density lipoprotein (... |
